The Cannigma

JANUARY 13, 2023

Based on the limited existing evidence, the best cannabis strain for migraines may be a Type II that includes both THC and CBD, and a terpene profile that includes beta-caryophyllene, myrcene, linalool, limonene, bisabolol, humulene or pinene. 5 THC and migraines THC is well-known for its anti-nausea and pain-relieving effects.

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MedicalJane

MAY 21, 2020

Researchers at The University of New Mexico (UNM) have conducted a series of recent studies testing the effectiveness and safety of consuming cannabis, but this is the first study they have conducted measuring the therapeutic potential of hemp oil with low THC levels. Westlund, Department of Anesthesiology.

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Puff Puff Post

JANUARY 13, 2020

Generally speaking, 99 cent stores sell CBD that doesn’t have its terpenes or other cannabinoids measured. Terpenes are the chemicals that give cannabis varieties their unique flavor or scent. Terpenes interact with both cannabidiol and THC and change the effects that either drug has on the body. Physicians at Mt.

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CBD Clinical Trials Research and Development Oil 52

Puff Puff Post

JANUARY 13, 2020

Generally speaking, 99 cent stores sell CBD that doesn’t have its terpenes or other cannabinoids measured. Terpenes are the chemicals that give cannabis varieties their unique flavor or scent. Terpenes interact with both cannabidiol and THC and change the effects that either drug has on the body. Physicians at Mt.

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CBD Clinical Trials Research and Development Oil 52

MMJ Recs

DECEMBER 28, 2023

THC, the psychoactive component of cannabis, has analgesic properties that can help manage chronic pain conditions, such as neuropathic pain and arthritis. Strains with a balanced THC and CBD ratio are often recommended for their synergistic effects in pain relief without the intense psychoactive experience.

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Conditions Chronic Pain Epilepsy Research and Development 98

The Cannigma

JULY 1, 2022

Because of this variability in the plant, and because of a lack of standard methods–like chemical analyses of cannabinoids or terpenes–has led to inconsistent scientific results. This is because these types of studies control the most variables to ensure that the results that come out of the trial are as reliable as possible.

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Research and Development Data THC Clinical Trials 108

Veriheal

APRIL 11, 2022

In particular, of all the components contained in the cannabis plant— including cannabinoids , terpenes , and flavonoids — the cannabis compound tetrahydrocannabinol (THC) has proven to harbor medicinal benefits when used in specific formulations.

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Pharmaceutical Research and Development DEA Clinical Trials 104

CannaMD

SEPTEMBER 28, 2020

Modern scientists are looking at the effects of both delta-9-tetrahydrocannabinol ( THC ) and cannabidiol ( CBD ) on sleep. High-THC strains often induce sleep and reduce the time it takes a person to fall asleep; however, many people don’t want the accompanying intoxicating effect. Trying Medical Marijuana.

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Sleep Clinical Trials Patients THC 73

The Cannigma

JUNE 24, 2021

For instance when it comes to pain relief, THC and CBD have shown to be safer than opioids; and for anti-anxiety and sleep aids, CBD does not appear to be habit-forming like benzodiazepines. This can mean taking a small amount of THC each day — for instance in the form of an edible — just to take the edge off and not to get intoxicated.

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CBD Microdosing Edibles Sleep 75

The Joint Blog

JANUARY 23, 2020

” The systematic review of the literature “was conducted during 2019, assessing the data from all case studies and clinical trials involving medicinal cannabis or plant-derived isolates for all major psychiatric disorders (neurological conditions and pain were omitted).”

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Clinical Trials Sleep Marijuana Cannabinoids 52

Miss Marijuana

MARCH 15, 2021

Although there are some phenotypes that have higher THC percentages, this flower is bursting with a high percentage of CBD. The rich smell provided by the pinene and myrcene terpenes make this flower a breath of fresh air for those looking for a strain with earthy tones for the nostrils. Ringo’s Gift at a glance: Effects. Common Use.

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Greencamp

AUGUST 16, 2018

This is how the psychoactive intoxication with THC affects our brain, and this same pathway is activated for the many other medical benefits cannabis has to offer. The only upside of dronabinol is that it can be a THC substitute where cannabis isn’t legalized, but besides that it is a very poor alternative to the real thing.

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Strains Cannabinoids Research and Development Indica 94

SpeedWeed

AUGUST 4, 2021

With a focus on high THC products, MCA is capable of producing high quality cannabis at very competitive pricing, which will in turn mean that we are helping more patients and really changing lives. MCA will continue to focus on the development of brands and products, with a focus on high-THC products. Courtesy of Sharon Bentley.

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Chronic Pain Research and Development Medicine Supply Chain 52

The Cannigma

JUNE 15, 2021

THC is by far the most abundant and popular molecule in marijuana. The two most well known and common cannabinoids are THC and CBD, and while they won’t alter the aroma and colors of cannabis, they do interact with numerous receptor systems in the human body and have a range of effects. CBD vs THC. CBD vs CBDA.

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CBD Research and Development Epilepsy Extraction 122

Sensi Seeds

NOVEMBER 23, 2018

This could well be caused by THC in particular – remember that the brain has a huge concentration of CB1 receptors, more than any other type of neuron, and these are activated by THC. For cannabis specifically, these are the cerebellum, the right frontal lobe, and the left temporal lobe. Cannabis increases blood flow to these areas.

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Blood Pressure Indica Clinical Trials Sativa 81

CannaMD

AUGUST 8, 2020

But CBD’s stolen the spotlight, partially because of its good cop/bad cop relationship with another famous cannabinoid: T etrahydrocannabinol or THC. THC is responsible for marijuana’s psychoactive effects. If you feel “high,” THC’s usually to blame. CBD Scheduling Rule Change.

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FloridaMarijuana.net

OCTOBER 9, 2018

In 2017, The National Academies of Sciences, Engineering, and Medicine published a statement that the use of cannabis for the treatment of pain is supported by “well-controlled clinical trials and that there is substantial evidence that cannabis is an effective treatment for chronic pain in adults.”.

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Terpenes Chronic Pain Strains Clinical Trials 100

Project CBD

OCTOBER 26, 2023

There is a growing body of anecdotal and scientific evidence that the “major cannabinoids” tetrahydrocannabinol (THC) and cannabidiol (CBD), certain “minor cannabinoids” (some without a name), and other cannabis compounds have antineoplastic action against cancer cells. THC binds to two types of cannabinoid receptors, CB1 and CB2.

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Research and Development Cannabinoids Terpenes Pharmaceutical 343

The Cannigma

DECEMBER 12, 2022

Just as THCA in cannabis flower needs to be decarboxylated into the active compound THC, psilocybin is not active until it undergoes a chemical reaction. Clinical research: Research is focusing on 5-MeO-DMT use in depression and anxiety. As such, there have been numerous clinical trials using ketamine.

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History Microdosing Research and Development Clinical Trials 119

Veriheal

SEPTEMBER 6, 2022

Recent research has found that terpene and cannabinoid profiles are far more significant when trying to produce specific effects. Delta-9 tetrahydrocannabinol (THC) may decrease sleep latency (e.g., Terpene and cannabinoid profiles of the cannabis you are consuming will also impact the effects experienced. Body weight.

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Sleep THC CBD Chronic Pain 108

Otherside Farms

NOVEMBER 3, 2019

CBD isolate is the perfect example of the absence of the entourage effect, and that’s why people are beginning to enhance it with terpenes. It is a non-psychoactive cannabinoid that modulates the effect of psychoactive THC. The second most talked-about aspect of the entourage effect is how it is affected by terpenes.

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Terpenes CBD Research and Development Cannabinoids 58

Project CBD

MAY 3, 2023

Dr. Goldstein: It appears that CBG does a lot of things that THC does and a lot of things that CBD does — but maybe even a little bit better. It’s kind of a bridge between THC and CBD. CannMed: It’s interesting that you say CBG is a bridge between THC and CBD. CBG is not intoxicating or impairing.

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Cannabinoids Sleep Clinical Trials CBD 209

Green Relief

MAY 13, 2018

government-held patent pertaining to “cannabinoids as antioxidants and neuroprotectants,” CBD and THC can limit “neurological damage following ischemic insults, such as stroke or trauma.”. CBD produces no intoxicating effects, no THC -like high, and its use does not lead to tolerance. Highlights: According to a U.S.

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THC CBD Cannabinoids Research and Development 64

Alchimia

JANUARY 25, 2022

Assuming clinical trials go well, the ultimate hope of the researchers is to develop a pill containing purified versions of these acidic cannabinoids as an adjunct to vaccination, for use after known exposure or by those who are immunocompromised. Why does CBD work best when combined with other cannabinoids and terpenes?

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Research and Development Terpenes CBD Treatment 98

The Cannigma

APRIL 8, 2021

Now, you’re talking about just 12 potential active therapeutic cannabinoids, then you can talk about, do the same thing through terpenes. Just like, people are consuming more THC than they need to achieve their desired effects and that leads to more side effects. MSO: What’s the biggest mistake that you see people making with cannabis?

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Medicine Cannabinoids Cannabis THC 108

Cannabis Law Report

AUGUST 12, 2019

Broad spectrum CBD oil contains a variety of active compounds such as cannabinoids and terpenes, which we will discuss in greater detail in Section 2. Marijuana is high in the psychoactive compound THC, or delta-9 tetrahydrocannabinol, the compound in marijuana that causes a high. The Differences Between Hemp and Marijuana.

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The Joint Blog

FEBRUARY 18, 2020

” Clinical trial data published in 2017 in in the journal European Neuropsychopharmacology previously reported that the administration of whole-plant cannabis extracts is associated with improvements in cognition and behavior in subjects with ADHD. 9-tetrahydrocannabinol (THC).

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The Cannigma

FEBRUARY 11, 2021

Listen & Subscribe: When Mara Gordon started using medical cannabis there wasn’t any lab testing — or any way to know how much of each cannabinoid or terpene was in a given strain. You know, started doing clinical trials through Zelda Therapeutics, and all the other things I’ve done. So I just started doing it myself.

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Wellness and Beauty Data Patients Medicine 125

Green Relief

MAY 12, 2018

government-held patent pertaining to “cannabinoids as antioxidants and neuroprotectants,” CBD and THC can limit “neurological damage following ischemic insults, such as stroke or trauma.”. CBD produces no intoxicating effects, no THC -like high, and its use does not lead to tolerance. Highlights: According to a U.S.

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Research and Development Cannabinoids Therapy CBD 40

Project CBD

NOVEMBER 11, 2023

Some years ago, our government allowed the use of Marinol, which is synthetic THC, especially for cancer patients. We rate levels of evidence, and a high level may be a controlled randomized clinical trial (RCT), but there are also observational studies. I think it’s more useful when THC is also present.

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Medicine Research and Development Pharmaceutical Cannabis 301

The Cannigma

MARCH 12, 2021

And he’s looking at it and all these words are coming out, cannabinoids, THC, CBD, ratios, terpenes, and the customer realizes they have no idea what they’re doing. So, the strains that are very popular in the rec world are almost exclusively the high THC products.

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Legalization Patients Education Dispensary 128

The Cannigma

DECEMBER 22, 2021

For example, when they open up the CBD-only market, products that will not contain THC, then they will probably find a solution there. We do participate in clinical trials that are initiated by others, and we will have our own clinical trial using terpene formulations in oil. We have, I think, eight PhDs.

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Research and Development Oil Cannabis Clinical Trials 79

The Cannigma

JULY 20, 2021

With this method, you’ll be looking at the most dominant cannabinoids and terpenes in a given cannabis plant, and will choose your cannabis based on their known properties. Broadly speaking, there are three types of cannabis chemotypes: Type I- High THC – Low CBD Type II- Balanced (roughly 1:1) THC-CBD ratio Type III- High CBD – low THC.

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Strains Terpenes Concentrates THC 145

Cannabis Law Report

NOVEMBER 24, 2021

The recreational use of cannabis is well known and attributed to its power as a psychotropic plant, specifically due to the cannabinoid tetrahydrocannabinol (THC). The TGA regulations permit applications for most cannabis products but nevertheless distinguish between cannabis products based on CBD and THC. 142), and “THC” ( n ?=?106)

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Cannabis Law Report

JULY 12, 2019

Recent studies on the effectiveness of cannabidiol in the rare seizure disorders Dravet Syndrome and Lennox-Gastaut syndrome have prompted a biopharmaceutical company to perform clinical trials of its own to bring a cannabidiol based drug to the American market through the process of FDA approval. Fig 1: Sucralose (In Study).

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Extraction Pharmaceutical CBD Epilepsy 73

Freedom Leaf

JANUARY 10, 2018

In fact, THC and various other compounds in the cannabis plant were discovered in Israel by now 87-year-old chemist Raphael Mechoulam, who continues to work at Hebrew University in Jerusalem. We’re also continuing to do some other clinical trials in Israel, specifically with our strains.” the efficacy of our strains.”

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Research and Development Clinical Trials Strains Patients 49

Cannabis Law Report

OCTOBER 29, 2019

Wakshlag is well-known in the veterinary medicine community as the first doctor to conduct an efficacy study in dogs in a clinical trial at Cornell using ElleVet CBD/CBDA on dogs with multi-joint discomfort. The clinical trial results confirmed more than 80% of dogs showed significant or dramatic improvement.

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Safety CBD Clinical Trials Oil 45