Clinical Trial: Oral THC Administration Associated with Opioid-Sparing Effects

NORML

Trauma patients administered oral THC consume fewer opioids than do similarly matched controls, according to clinical trial data published in the journal Trauma Surgery & Acute Care.

Clinical Trial: CBD Administration Reduces Heroin Cravings

NORML

The administration of oral CBD reduces cue-induced cravings and anxiety in subjects with a history of heroin use, according to clinical data published in The American Journal of Psychiatry. In clinical models, CBD administration has been shown to reduce cravings for tobacco. Investigators at The Mount Sinai Health System in New York City assessed the effect of CBD versus placebo in 42 drug-abstinent participants with a history of heroin use.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Clinical Trial: Cannabinoid Administration Via a Metered-Dose Inhaler Is Safe and Effective for Chronic Pain Patients

NORML

The delivery of precise doses of THC via an inhaler is associated with pain mitigation in patients with neuropathy and other complex pain conditions, according to clinical trial data published in the European Journal of Pain.

Japanese Officials Approve Epidiolex For Clinical Trials

Cannabis Law Report

The trials, to be tightly controlled in a hospital environment, are exempted from Japan’s Cannabis Control Act, which bans cannabis compounds generally. Japanese officials approve Epidiolex for clinical trials.

Clinical Trial: Transdermal Application of CBD Effective in Patients with Myofascial Pain

NORML

The transdermal application of plant-derived CBD reduces fascial pain in patients with temporomandibular disorders (TMD aka TMJ), according to clinical data published in the Journal of Clinical Medicine. Polish investigators conducted a randomized, double-blind placebo-controlled trial assessing the efficacy of twice-daily transdermal CBD administration on 60 patients with TMD over a period of 14 days.

InMed Pharmaceuticals Announces Completed Enrollment in Phase 1 Clinical Trial of INM-755 CBN Cream in Healthy Subjects

Puff Puff Post

“We are very pleased with the rapid completion of enrollment achieved by the team at the Centre for Human Drug Research (CHDR) in Leiden, the Netherlands,” said Alexandra Mancini, InMed’s Senior Vice President of Clinical Development & Regulatory Affairs.

FDA Approves Marijuana-Based Epilepsy Drug For Use On Kids In Clinical Trials

Otherside Farms

Federal regulators have approved two clinical studies testing whether a marijuana-based epilepsy drug may help prevent seizures among epileptic children. Source: FDA Approves Marijuana-Based Epilepsy Drug For Use On Kids In Clinical Trials.

Are Marijuana Inhalers Most Effective Treatment For Chronic Pain?

The Fresh Toast

Cannabis Medical Marijuana News RX cannabis inhalers chronic pain clinical trials Neuropathy THCAre Marijuana Inhalers Most Effective Treatment For Chronic Pain?

InMed Submits Clinical Trial Application to Evaluate INM-755 in Phase 1 Trial

Puff Puff Post

5, 2019 /CNW/ – InMed Pharmaceuticals Inc. (“InMed” or the “Company”) (TSX: IN; OTCQX: IMLFF), today announced the filing of a Clinical Trial Application (“CTA”) in the Netherlands to initiate a Phase 1 human clinical trial for INM-755 in healthy volunteers.

CBD for Brain-Damaged Babies?

Project CBD

The launch of a clinical trial examining the use of CBD in newborns suffering from hypoxic ischemic encephalopathy (brain damage caused by lack of oxygen) means new hope for the million plus babies born each year with this condition

Cannabinoids for Scleroderma

Project CBD

Two compounds that target the endocannabinoid system are currently in development to treat scleroderma – and they’re already in clinical trials.

Hooked on Weed? Try Nicotine Instead

Project CBD

Recently NIDA supported a clinical trial which used nicotine as a therapy for relatively mild cannabis withdrawal symptoms

The Best Organic CBD Oil in the UK

Cannabis Law Report

AS CBD continues to go from strength to strength, both in clinical trials and in the minds of the mainstream, the question of the best … Read More.

Today’s Answer of the Day

TheAnswerPage

Are any pre-clinical trials or clinical trials evaluating the therapeutic benefits of CBD currently underway?

Marijuana Shows Promise In Sickle Cell Disease Treatment

The Fresh Toast

Clinical trial results indicate cannabis could provide an alternative or adjunctive treatment to sickle cell patients. Marijuana Shows Promise In Sickle Cell Disease Treatment.

US Government Approves Increased Production of Marijuana for Clinical Research

NORML

Federal officials have approved plans for the University of Mississippi to grow 2,000 kilograms (4,409 pounds) of cannabis to provide to investigators for clinical trial research.

Today’s Answer of the Day

TheAnswerPage

Excluding potential drug:drug interactions, what adverse effects of CBD have been noted in clinical trials? In clinical trials evaluating CBD, adverse effects, including diarrhea, somnolence, decreased appetite, change in weight, and increased levels of liver enzymes have been noted.

Brain Awareness Week: CBD and the Brain

Leafwell

Cannabidiol (CBD) is still a big mystery in many ways.

Today’s Answer of the Day

TheAnswerPage

Is the US VA Office of research and Development conducting any clinical trials that evaluate the use of CBD for the treatment of PTSD? The trial will compare PE + CBD to PE + placebo in a sample of 136 military Veterans with PTSD at the VA San Diego Medical Center.

CDC Seeks Public Comments Regarding Chronic Pain Management

NORML

” This finding is hardly a surprise, as cannabis is well-established to mitigate pain in clinical models, particularly in patients with neuropathy.

Today’s Answer of the Day

TheAnswerPage

Transporting [marijuana] across states lines may not be lawful under state laws, unless a patient is participating in a clinical trial and has a letter that documents such participation.”

Cannabis 3.0 Accelerates Access to Consumer and Medical Research

Cannabis Law Report

Virtual Clinical Trials transcend geographic, mobility and economic barriers. Clinical trials are medical research projects involving human participants. The opportunity of virtual clinical trials appears to meet all of these criteria.

Review Paper: Clinical Evidence Lacking in Support of CBD as an Anti-Viral Agent

NORML

There is an absence of clinical data supporting the efficacy of CBD as an antiviral agent, according to a systematic literature review published in the journal Cannabis and Cannabinoid Research.

UK: NHS – The Minimalist Approach To Issuing Cannabis Reimbursements

Cannabis Law Report

Since a new law took effect a year ago, England’s National Health Service (NHS) has reimbursed patients on only 18 occasions for “unlicensed” cannabis-based products that have not undergone clinical trials, according to government data.

Today’s Answer of the Day

TheAnswerPage

Do the results of randomized clinical trials support those claims? According to reports in the media and statements on various CBD websites, CBD has anti-depressant effects.

Legislation To Produce And Research Cannabis Introduced

NORML

A bipartisan coalition of House lawmakers has introduced The Medical Cannabis Research Act of 2019 ( HR 601 ), to facilitate federally-approved clinical trials involving cannabis. The act ends the University of Mississippi’s existing monopoly on the growth of cannabis for clinical research purposes, by requiring the licensing of additional manufacturers.

Canadian Researchers Studying Hemp Protein to Treat Hypertension

Leafly

"If the clinical trial shows that hemp can help reduce blood pressure, then other treatment areas will be examined.". The post Canadian Researchers Studying Hemp Protein to Treat Hypertension appeared first on Leafly. Canada Health Science & Tech Hemp research studies

ASA offers solution to DOJ research block: Our comments on the DEA’s proposed rules

Americans for Safe Access

On March 23, DEA published a proposed rulemaking —“Controls to Enhance the Cultivation of Marihuana for Research in the United States”—in the Federal Register (85 FR 16292), involving who can grow cannabis in bulk for research purposes.

Study: Marijuana Provided For FDA-Approved Clinical Research Genetically Similar to Hemp

NORML

Marijuana grown by the University of Mississippi for clinical research purposes is genetically divergent from strains of cannabis commercially available in retail markets, according to an analysis prepared by researchers at the University of Northern Colorado.

Today’s Answer of the Day

TheAnswerPage

Have the results of CLINICAL studies also shown that cannabinoids are effective at alleviating acute and chronic pain? In contrast to experimental studies, the results of clinical trials with cannabinoids provide only moderate-quality evidence for the relief of chronic pain.

Not-very-NICE: UK Cannabis Policy and Harm to Patients

CannaTech

This commentary on the NICE UK cannabis guidelines is originally published by The Academy of Medical Cannabis , the globally leading institute for clinical training and research in cannabis-based medicinal products.

Today’s Answer of the Day

TheAnswerPage

Is the US VA Office of research and Development conducting any clinical trials that evaluate the use of CBD for the treatment of PTSD? The trial will compare PE + CBD to PE + placebo in a sample of 136 military Veterans with PTSD at the VA San Diego Medical Center.

Kristin & Shelby – Fighting Dravet Syndrome

Leafwell

This is how Kristin Wilcox describes the effect a cannabis-infused drug given to her daughter, Shelby Mathews, during a clinical trial on cannabinoids for Dravet Syndrome. “I saw a change almost immediately. I can’t even explain … I can’t even describe it, but it was … It was like a light started coming back into her eyes.”

Today’s Answer of the Day

TheAnswerPage

What adverse effects of CBD have been noted in clinical trials? In clinical trials evaluating CBD, adverse effects, including diarrhea, somnolence, decreased appetite, and increased levels of liver enzymes have been noted.

New Study Aims To Learn If Cannabis Can Help Treat Autism

MedicalJane

The United States Department of Defense and GW Pharmaceuticals are collaborating on a new clinical trial at the Montefiore Medical Center in New York. The CBDV compound for the trial is being shipped from the United Kingdom to Dr. Eric Hollander.

EU Parliament Publish Procedure File & Resolution On, “Use of cannabis for medicinal purposes”

Cannabis Law Report

Ensure that safe and controlled cannabis used for medicinal purposes can only be in the form of cannabis-derived products that have gone through clinical trials, regulatory assessment and approval.”. Here are some of the bullets from the resolution.

Survey: Three Of Four Military Veterans Would Consider Using Medical Cannabis

NORML

Proposed federal legislation to direct the agency to conduct clinical trials on the use of cannabis for PTSD and for other conditions is currently pending in the US House and Senate. Seventy-five percent of military veterans say that they would consider using either “cannabis or cannabinoid products as a treatment option,” according to member survey data compiled by the group Iraq and Afghanistan Veterans of America (IAVA).