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CBD Topical Medicine: What Does the Science Say?

Project CBD

Consider it a testament to the ubiquity and flexibility of the endocannabinoid system: we can inhale medicinal cannabinoids via combustion or vaporization; ingest them via food or drink; and absorb them directly through the skin, the bodys largest organ. This latter category is broader and more complex than many of us give it credit for.

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Medical Marijuana Offers Hope for Treatment of PTSD

FloridaMarijuana.net

Evidence-based Complementary and Alternative Medicine published an article titled “Post-Traumatic Stress Disorder: Evidence-Based Research for the Third Millennium” which describes how profound the symptoms of PTSD can be: “Traumatic events are profoundly stressful.

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Cannabinoids: THC

FloridaMarijuana.net

A 2006 edition of Current Pharmacology published an article titled: “Role of the Cannabinoid System in Pain Control and Therapeutic Implications for the Management of Acute and Chronic Pain Episodes”. Cannabinoid Receptors , referred to as CB1 and CB2, are an essential part of the human body’s endocannabinoid system.

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Cannabinoids for Tinnitus?

Project CBD

All but two of the 45 respondents said they’d consider cannabis as a treatment, with 29 seeking help for sleep disturbances, 27 for emotional complaints, 25 for functional disturbances, and nine for pain. There could be a role for cannabinoids in the management of tinnitus through their anticonvulsant effects. And its conclusion?

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Quick Hits

Project CBD

In his first article of the new year, Raphael Mechoulam and other Israeli scientists look at the “real life experiences of medical cannabis treatment in autism.” Around 10-20% of patients stopped taking various medications (mostly antipsychotic and antiepileptic drugs) within 6 months of starting cannabis treatment.

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CBD Enhances Glucose Metabolism via Nuclear Receptors

Project CBD

Cannabinoid receptors CB1 and CB2 are the definitive and best-known targets of endogenous and plant-derived cannabinoids, but they’re far from the only ones. Two recent papers reiterate the point that to really understand cannabinoids (especially CBD) and the ECS, it’s essential to get to know the PPARs. And it worked.

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Which Terpenes Enhance the Cannabis High?

Project CBD

Ten years ago, most cannabis consumers couldn’t tell a terpene from a cannabinoid. A 2021 study 2 by University of Arizona scientists concluded that certain terpenes are “cannabimimetic” (in a mouse model of cannabis intoxication) and can selectively enhance cannabinoid activity. But today things are different.

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