The Cannigma

MARCH 7, 2022

When CBN was studied without barbiturates (prescription sedative medications typically used for epilepsy), the combination of CBN and THC produced greater sedation together than either cannabinoid alone. What can the current clinical trials tell us? Common cannabinoids in cannabis.

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THC Sleep Clinical Trials Cannabinoids 140

The Cannigma

MAY 19, 2021

In 2019, Japan approved clinical trials for Epidiolox — a cannabis derived medicine used to treat severe forms of childhood epilepsy such as Dravet and Lennox-Gastaut syndromes. CBD has become especially trendy in Tokyo, where CBD shops and cafes allow for the on-site consumption of CBD in edibles and topical treatments.

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Law Legalization Clinical Trials CBD 137

Cannabis Law Report

SEPTEMBER 6, 2021

Clinical trials, research and development (R&D) activities and commercialization of cannabis-based indications are further expected to catalyze the growth of the market. Key Topics Covered: 1 Preface. 12 Overview of Clinical Research Suggesting the Benefits of Medical Cannabis Across Various Indications. Chronic Pain.

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Chronic Pain Research and Development Clinical Trials Epilepsy 86

Cannabis Law Report

JUNE 7, 2022

Did you know that CBD is approved to treat seizures caused by different types of epilepsy? This was when clinical trials found a significant reduction in seizures for people who took CBD. There are CBD oils, topicals, and one of the best ways to consume the chemical: edibles. Alleviates Seizures.

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Chronic Pain CBD Digestion Edibles 52

Kind Meds (Cannabis Education Blog)

NOVEMBER 18, 2020

CBD is also available in conventional pill and tablet form, as a base to use for cooking, and in topical products. When it comes to using CBD for anxiety, most clinical trials involved using very highly concentrated CBD, and there are no known severe adverse effects of consuming “too much” CBD.

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Treatment Conditions CBD Clinical Trials 111

The Joint Blog

APRIL 22, 2022

There are multiple ways to ingest this oil; one can apply it topically, consume it through smoke inhalation or in the form of edible. Consumption of CBD through smoke inhalation or ingestion is beneficial for treating widespread pain, while topical application is recommended for alleviating pain from a specific area. Treats Epilepsy.

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Oil CBD Topical Clinical Trials 26

Canna Care Docs

DECEMBER 16, 2020

Medical cannabis is available in any of the same forms as recreational cannabis—as smokable flower, edibles , tinctures, topical products , and more. Cannabis appears to have strong benefits for people struggling with epilepsy, with a 2015 study finding a 54% reduction in seizures for patients who were not helped by other treatments.

Chronic Pain 52

Chronic Pain Marijuana Clinical Trials Epilepsy 52

CannaTech

SEPTEMBER 16, 2018

Many healthcare practitioners possess a knowledge gap about cannabis, as their medical school curriculum didn’t include any information on the topic. Over time extended clinical trials will continue to map out the plant’s therapeutic effects, supporting it as an alternative medicine offering relief for a long list of conditions.

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Education Medicine Clinical Trials Patients 66

The Cannigma

JUNE 15, 2021

The first clinical research done on CBD as a potential treatment for epilepsy was in 1980, but the information gleaned didn’t make its way to the public eye until decades later. The perception that CBD is a wonder-drug version of cannabis — particularly known for its uses to treat epilepsy — that doesn’t get you high.

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CBD Research and Development Epilepsy Extraction 122

Kind Meds (Cannabis Education Blog)

JANUARY 9, 2019

Epidiolex has received FDA approval to treat Dravet Syndrome and Lennox-Gestaut Syndrome; two very rare forms of epilepsy that manifest in early childhood. The only side effects reported from Epidiolex clinical trials were sleepiness, sedation, insomnia, fatigue, diarrhea, rash, and some infections.

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Research and Development Treatment Pharmaceutical Conditions 97

MMJ Recs

DECEMBER 22, 2023

Medical marijuana, once a controversial and stigmatized topic, has undergone a remarkable transformation in the eyes of the American public. Studies have shown the efficacy of medical cannabis in treating conditions such as chronic pain, epilepsy, and certain mental health disorders.

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Marijuana Chronic Pain Advocacy Research and Development 52

Kind Meds (Cannabis Education Blog)

NOVEMBER 16, 2022

capsule, oil, topical, edible). When CBN cream is applied to the skin of clinical trial participants, it appears to be beneficial in treating epidermolysis bullosa, a rare disease that causes blisters on the skin. CBN is believed to relieve symptoms of conditions in which seizures are a symptom, including epilepsy.

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Sleep Cannabinoids THC CBD 94

Cannabis Law Report

FEBRUARY 3, 2022

Based on route of administration, the market is segmented into oral, topical, inhalation, rectal, sublingual. CBD oils have various health benefits in treating medical disorders like epilepsy, anxiety, cancer, acne, diabetes, and others. Clinical Trials of Cannabis Are Still on Going. German Narcotics Act. 2564 (2021).

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Indica Oil Legalization Research and Development 52

Cannabis Law Report

SEPTEMBER 28, 2021

DUBLIN–(BUSINESS WIRE)–The “Epilepsy – Pipeline Insight, 2021” clinical trials has been added to ResearchAndMarkets.com’s offering. This Epilepsy – Pipeline Insight, 2021 provides comprehensive insights about 70+ companies and 70+ pipeline drugs in Epilepsy pipeline landscape.

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Epilepsy Clinical Trials Research and Development Pharmaceutical 52

Greencamp

AUGUST 16, 2018

The CBD cannabinoid is proven to be an exceptional seizure-controlling agent for epilepsy patients, and also shows great promise for treating Parkinson’s , Alzheimer’s and Multiple Sclerosis. Marijuana and Epilepsy: Here’s How Cannabis Stops Seizures (12 Studies). Exploring the available research on ALS and cannabinoids.

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Strains Cannabinoids Research and Development Indica 94

Cannabis Law Report

JANUARY 24, 2022

Key Topics Covered: Chapter 1 Methodology and Scope. North America Legal Cannabis Number of clinical trials. North America Legal Cannabis Number of clinical trials. Chapter 2 Executive Summary. Chapter 3 North America Legal Cannabis Market: Variables, Trends & Scope. Market Segmentation. Market Dynamics.

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Legalization Supply Chain Chronic Pain Recreational 52

Cannabis Law Report

DECEMBER 20, 2021

(“Virpax” or the “Company”) (NASDAQ: VRPX), a company specializing in developing product candidates for pain management, CNS disorders and anti-viral indications, signed a clinical trial agreement with Altasciences Company, Inc., Virpax is initially seeking FDA approval of its three patented drug delivery platforms. About Altasciences.

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Clinical Trials Chronic Pain Pharmaceutical Data 52

Cannabis Law Report

SEPTEMBER 20, 2021

Nanomerics”) to use Nanomeric’s molecular envelope platform technology (MET) for the nasal delivery of a cannabidiol (CBD) for the management of epilepsy in adults and children. Epoladerm™ is a topical diclofenac metered-dose spray film formulation being developed to manage acute musculoskeletal pain and osteoarthritis.

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Epilepsy Research and Development Clinical Trials Chronic Pain 52

Project CBD

FEBRUARY 28, 2023

5 In June 2018, the FDA approved Epidiolex® (GW Pharmaceuticals; Cambridge, UK), the first FDA-approved pharmaceutical drug to contain a “purified drug substance [CBD] derived from marijuana,” for the treatment of seizures associated with two rare epilepsy disorders. Epilepsy Behav. Available at: www.fda.gov/media/131878/download.

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CBD Seed-To-Sale Food Access 144

MGC Pharma

FEBRUARY 20, 2018

Cannabis is an effective tool for the treatment of topical skin conditions In a recent study by undertaken by MGC Pharma, our dermatologists found that CBD is effective in providing relief for relief for dry, red, flakey, oily and acne prone skin through CBD skincare.

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Research and Development Clinical Trials Patients Chronic Pain 100

Cannabis Law Report

OCTOBER 6, 2021

With the additional funding recently secured by Virpax and the strengthening of our balance sheet, we are continuing to advance our product candidates and to move them through preclinical studies and into human clinical trials,” said Anthony Mack, Chairman and Chief Executive Officer of Virpax Pharmaceuticals.

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Research and Development Clinical Trials Pharmaceutical Chronic Pain 52

Cannabis Law Report

DECEMBER 8, 2021

Charles River Laboratories, a renowned CRO engaged by Virpax to perform Food and Drug Administration (FDA) required pre-clinical studies, has completed a single dose pharmacokinetic study of dermal administration of Epoladerm in minipigs as part of the required Investigational New Drug Application (“IND”) enabling trials.

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Clinical Trials Chronic Pain Pharmaceutical Topical 52

CannaTech

SEPTEMBER 23, 2019

NICE develop evidence-based guidelines on a wide range of health-related topics, including integrating novel and emerging therapies. Last week NICE released the first draft of their evidence-based guidelines, concluding it could not recommend CBMPs for routine use because of high cost and a dearth of clinical trial evidence.

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Patients Policy Clinical Trials Research and Development 79

Cannabis Law Report

DECEMBER 28, 2021

We added VRP324 which is an intranasally delivered cannabidiol (‘CBD’) formulation for the management of epilepsy in adults and children. Epoladerm™ Epoladerm is a diclofenac topical spray film product candidate that is being developed for pain associated with osteoarthritis of the knee. to conduct this study in Canada.

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Pharmaceutical Research and Development Clinical Trials Chronic Pain 52

Cannabis Law Report

NOVEMBER 15, 2021

Finally, we recently acquired the worldwide rights to VRP324, which is an intranasal pharmaceutical-grade cannabidiol product candidate for the management of epilepsy in children (rare pediatric disease) and adults. Epoladerm™ is a topical diclofenac spray film formulation being developed to manage osteoarthritis pain.

Pharmaceutical 52

Pharmaceutical Research and Development Clinical Trials Chronic Pain 52

Cannabis Law Report

SEPTEMBER 9, 2021

Medical cannabis is used for the treatment of various chronic conditions, such as Parkinson’s disease, Alzheimer’s disease, arthritis, cancer, depression, anxiety, epilepsy, and other neurological conditions. Key Topics Covered: Chapter 1 Methodology and Scope. Chapter 2 Executive Summary. Market Segmentation. Switzerland.

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Recreational Hemp THC Legalization 95

Cannabis Law Report

OCTOBER 1, 2021

Epoladerm™ is a topical diclofenac metered-dose spray film formulation being developed to manage acute musculoskeletal pain and osteoarthritis. Virpax is developing branded, non-addictive pain management and neurological product candidates using its proprietary technologies to optimize and target drug delivery.

Research and Development 52

Research and Development Pharmaceutical Clinical Trials Chronic Pain 52

Cannabis Law Report

NOVEMBER 10, 2021

Epoladerm™ is a topical diclofenac spray film formulation being developed to manage osteoarthritis pain. Virpax recently acquired global rights to VRP324, a product candidate for the nasal delivery of a pharmaceutical-grade cannabidiol (CBD) for the management of epilepsy in children (a rare pediatric disease) and adults.

Research and Development 52

Research and Development Chronic Pain Pharmaceutical Clinical Trials 52

Cannabis Law Report

NOVEMBER 24, 2021

Chronic pain or pain were the conditions most frequently mentioned in articles about cannabis, followed by epilepsy, cancer or cancer pain, and nausea and chemotherapy. It was also used as a topical treatment for haemorrhoids, ear infection, and wounds (Aldrich 1997 ; Touw 1981 ). Refractory paediatric epilepsy. Conclusions.

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Research and Development Medicine Access Media 52

The Cannigma

DECEMBER 22, 2021

We have autism and epilepsy. I don’t know if we’ll have topicals initially, or later on. We do participate in clinical trials that are initiated by others, and we will have our own clinical trial using terpene formulations in oil. Cannabis is given to oncology patients, palliative patients.

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Research and Development Oil Cannabis Clinical Trials 79

Cannabis Law Report

AUGUST 12, 2019

After multiphase clinical trials were completed, an FDA panel recommended approval of a CBD-based pharmaceutical called Epidiolex for treatment of certain specific and rare types of juvenile epilepsy. CBD-Infused Topicals. CBD-infused topicals include skin creams, balms, salves and oils.

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CBD Terpenes Oil Tincture 40

Cannabis Law Report

JULY 12, 2019

Recent studies on the effectiveness of cannabidiol in the rare seizure disorders Dravet Syndrome and Lennox-Gastaut syndrome have prompted a biopharmaceutical company to perform clinical trials of its own to bring a cannabidiol based drug to the American market through the process of FDA approval. Lancet Neurol Dec 23 2015. Fabricio A.

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Extraction Pharmaceutical CBD Epilepsy 73

Cannabis Law Report

OCTOBER 17, 2019

Retailers such as Walgreens, CVS, Rite Aid, Kroger, Safeway, Nordstrom, and DSW are selling or plan to sell CBD-infused topical lotions, cosmetics, and even edibles where they are legally able to do so. the form the finished product can take (edibles, topicals, etc.). how the segments are defined (e.g.,

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Law Seed-To-Sale Hemp Recreational 40