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The AHRQ Wants to Learn About Cannabis and Kratom For Chronic Pain

Veriheal

In adults with chronic pain , what are the harms of Kratom or other plant-based substances for treatment of chronic pain? In adults with chronic pain, what are the harms of cannabinoids? In adults with chronic pain, what are the benefits of cannabinoids?

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Beta-Caryophyllene: Terpene Powerhouse

Project CBD

Project CBD recently reported on studies indicating that cannabis terpenes — the compounds that give the plant its robust and distinctive smell — activate the CB1 cannabinoid receptor. What’s more, in the presence of THC (also a CB1 agonist), terpenes appear to modulate cannabinoid activity in varied and interesting ways.

Terpenes 227
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Answer of the Day for Dec 16, 2021

TheAnswerPage

When considering adding cannabinoid-based medications to a chronic pain patient’s medical regimen, what are some of the main factors that should be considered to inform recommendations? Medical cannabis or cannabinoids for chronic pain: a clinical practice guideline BMJ 2021; 374 :n2040 doi:10.1136/bmj.n2040.

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Answer of the Day for Oct 6, 2021

TheAnswerPage

What influences chronic pain patients’ use of medical cannabinoids? The British Medical Journal recently published results of a systematic review that explored values and preferences towards medical cannabis (MC) among people living with chronic pain. doi: 10.1136/bmjopen-2021-050831.

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Answer of the Day for Oct 8, 2021

TheAnswerPage

What are the mechanisms in which THC and CBD impact pain sensation? According to a British Medical Journal article published in Sept 2021, “THC inhibits glutamate and 5-hydroxytryptamine release and increases dopamine secretion. ” Medical cannabis or cannabinoids for chronic pain: a clinical practice guideline.

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Answer of the Day for Dec 17, 2021

TheAnswerPage

Medical cannabis or cannabinoids for chronic pain: a clinical practice guideline BMJ 2021; 374 :n2040 doi:10.1136/bmj.n2040. Other non-serious adverse events include nausea, sleepiness, confusion and anxiety. Busse J W, Vankrunkelsven P, Zeng L, Heen A F, Merglen A, Campbell F et al. See the Answer.

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Answer of the Day for Dec 14, 2021

TheAnswerPage

As a result, the transmission of pain signals is altered. Medical cannabis or cannabinoids for chronic pain: a clinical practice guideline BMJ 2021; 374 :n2040 doi:10.1136/bmj.n2040. Busse J W, Vankrunkelsven P, Zeng L, Heen A F, Merglen A, Campbell F et al. See the Answer.