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Risk factors span a wide range of physical and psychological conditions including concussion, smoking, certain medications, ear infection, high bloodpressure, anxiety, depression, and, most commonly, age-related hearing loss. There could be a role for cannabinoids in the management of tinnitus through their anticonvulsant effects.
Across the eight studies they analyzed, the Australia-based authors identified increased levels of oleoylethanolamide and stearoylethanolamide (endocannabinoid-like molecules called N-Acylethanolamines that don’t bind with the cannabinoid receptors) in patients with these conditions compared to controls. 22,7 (2006): 1269-76.
The percentage of Americans over 65 who had reported using cannabis in the past year had increased tenfold between 2006 to 2018, from 0.4% Even the American Association of Retired Persons (AARP) now supports the use of medical marijuana in states where it is legal and officially calls for more research on the medicinal use of cannabinoids. ?
Marijuana and Cannabinoids: Health, Research and Regulatory Considerations (Position Paper). 1 Simultaneously, the AAFP acknowledges preliminary evidence indicates marijuana and cannabinoids may have potential therapeutic benefits, while also recognizing subsequent negative public health and health outcomes associated with cannabis use.
Cannabis contains more than 421 different chemical compounds, including a group of more than 60 bioactive compounds (called cannabinoids). Cannabinoids in raw (unprocessed) cannabis plants include tetrahydrocannabinolic acid (THCA), which, with heat, time, and/or light transforms into THC, the main psychoactive compound of cannabis products.
International Cannabinoid Cancer Research Institute (Draft 5). This paper seeks to answer why refined cannabinoids have more side effects than the natural cannabis product, as well as the possible etiology of said adverse reactions. Also discussed are other attempts at affecting the cannabinoid system from a singular standpoint.
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