TheAnswerPage

AUGUST 27, 2022

“The Answer of the Day” series on the treatment effects of cannabinoids continues… According to randomized controlled trials, which health conditions does dronabinol (Marinol – a synthetic THC product) effectively treat? See the Answer. Spanagel, R. BMC Med 20, 259 (2022).

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TheAnswerPage

FEBRUARY 3, 2022

Be sure to read the next few Answers of the Day to find out more. See the Answer. Warfarin has numerous drug interactions. Does warfarin interact with marijuana? The metabolic enzyme CYP2C9 is responsible for metabolizing warfarin, and THC and CBD inhibit CYP2C9. Thomas, T.F., Metaxas, E.S., J Cannabis Res 4, 6 (2022).

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TheAnswerPage

AUGUST 28, 2022

“The Answer of the Day” series on the treatment effects of cannabinoids continues… According to randomized controlled trials, which health conditions does nabiximols (Sativex – ~50:50 THC:CBD plant-derived product) effectively treat? See the Answer. Spanagel, R. Spanagel, R. BMC Med 20, 259 (2022).

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TheAnswerPage

MAY 8, 2022

in excess of 150 mg/kg iv as an acute dose or in excess of 30 mg/kg orally daily for 90 days) were administered. See the Answer. World Health Organization (WHO) – Expert Committee on Drug Dependence Thirty-ninth Meeting Cannabidiol (CBD) Pre-Review Report Agenda Item 5.2 Geneva, 6-10 November 2017. Geneva, 6-10 November 2017.

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CBD 59

TheAnswerPage

JULY 22, 2022

The “Cannabinoid-based Medications for the Treatment of Chronic Pain” series continues… As described in the previous Answer of the Day, the September 9, 2021 edition of the British Medical Journal contained the guidelines entitled “Medical cannabis or cannabinoids for chronic pain: a clinical practice guideline.”

Chronic Pain 52

Chronic Pain Sleep Cannabinoids Therapy 52

TheAnswerPage

JULY 20, 2022

Today’s Answer of the Day is the first of a series of questions and answers focusing on the use of cannabinoid-based medications for the treatment of chronic pain. See the Answer. “Pain that persists or recurs for three months or more is defined as chronic.

Chronic Pain 52

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TheAnswerPage

AUGUST 26, 2022

This question begins “The Answer of the Day” series on the treatment effects of cannabinoids…. See the Answer. Has it been shown that any cannabinoids have a significant therapeutic effect on a health condition? Efficacy, retention and the adverse events of medical cannabinoids were examined. Spanagel, R.

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Cannabinoids Epilepsy Treatment Conditions 52

TheAnswerPage

AUGUST 19, 2022

CBD for post-operative pain continues… The results of a study evaluating the buccal administration of CBD (CBD absorbed through the cheek) have indicated that CBD decreases pain on day 1 after a shoulder arthroscopic procedure. See the Answer. Does the topical administration of CBD decrease pain after a knee arthroscopy? Apr 4, 2022.

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TheAnswerPage

MAY 6, 2021

See Answer. See Answer. Learn something every day ® right from your inbox. Sign up for The Answer of the Day email…. Do cannabinoids affect the function of the gastrointestinal system? Izzo AA, Sharkey KA. Cannabinoids and the gut: New developments and emerging concepts. Sign Up!

Digestion 59

Digestion Cannabinoids 59

TheAnswerPage

AUGUST 20, 2022

The study patients received 150 mg CBD oil twice daily for 8 days beginning 1 day before initiation of chemotherapy. See the Answer. Can oral cannabidiol help prevent acute and/or transient chemotherapy-induced peripheral neuropathy? Nielsen, S.W., Hasselsteen, S.D., Dominiak, H.S.H. Support Care Cancer (2022).

Patients 52

Patients Safety CBD Oil 52

TheAnswerPage

JUNE 1, 2021

in excess of 150 mg/kg iv as an acute dose or in excess of 30 mg/kg orally daily for 90 days) were administered. See the Answer. World Health Organization (WHO) – Expert Committee on Drug Dependence Thirty-ninth Meeting Cannabidiol (CBD) Pre-Review Report Agenda Item 5.2 Geneva, 6-10 November 2017. Geneva, 6-10 November 2017.

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CBD 72

TheAnswerPage

APRIL 28, 2021

See Answer. See Answer. Learn something every day ® right from your inbox. Sign up for The Answer of the Day email…. Kumar RN, Chambers WA, Pertwee RG. Pharmacological actions and therapeutic uses of cannabis and cannabinoids. Anaesthesia. 2001; 56: 1059-1068. Sign Up!

Chronic Pain 59

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TheAnswerPage

MAY 18, 2021

See Answer. See Answer. Learn something every day ® right from your inbox. Learn something every day ® right from your inbox. Sign up for The Answer of the Day email…. What percentage of US medical marijuana legal states list cancer as a qualifying condition? Weiss, Julianne Hibbs, Terri W. Sign Up!

Treatment 59

Treatment Cannabinoids Conditions Patients 59

TheAnswerPage

FEBRUARY 27, 2022

Read the next Answer of the Day to find out more.). See the Answer. Syndros and Marinol are both FDA-approved synthetic forms of delta-9-tetrhydrocannabinol (THC). In what dosage forms are these 2 products supplied? Marinol is available in capsule form while Syndros is available in a liquid form of THC.

Treatment 52

Treatment THC Patients 52

TheAnswerPage

MAY 12, 2021

See Answer. See Answer. Learn something every day ® right from your inbox. Sign up for The Answer of the Day email…. Sign up for The Answer of the Day email…. What CBD products, if any, have been evaluated and approved by the FDA? It is called Epidiolex. Sign Up!

Pets 59

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TheAnswerPage

MAY 15, 2021

See Answer. See Answer. Learn something every day ® right from your inbox. Sign up for The Answer of the Day email…. While Sativex® is approved in several European countries, Canada, and other countries, it has not been approved for medical use in the U.S. Brown JD, Winterstein AG. J Clin Med. 2019;8(7):989.

Events 59

Events THC CBD 59

TheAnswerPage

APRIL 29, 2021

See Answer. See Answer. Learn something every day ® right from your inbox. Sign up for The Answer of the Day email…. The cannabinoids act on the presynaptic CB1 receptors, and the receptor activation reduces massive glutamate release and regulates glutamatergic excitability during spasticity. Neurology 2014.

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TheAnswerPage

JANUARY 9, 2022

However, purified CBDV is currently being evaluated for other conditions, including as a treatment for behavioral symptoms in patients with Prader Willi Syndrome (10 mg/kg/day, NCT03848481) and in autism (NCT03202303 and NCT03849456). See the Answer. That trial did not continue. Schlag, A.K., O’Sullivan, S.E,

Clinical Trials 59

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TheAnswerPage

APRIL 27, 2021

See Answer. See Answer. Learn something every day ® right from your inbox. Sign up for The Answer of the Day email…. What is the pharmacokinetic profile of marijuana when it is smoked? Inhaled constituents quickly pass from alveoli into the bloodstream and readily cross the blood-brain barrier. Huestis MA.

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Cannabinoids THC CBD Marijuana 59

TheAnswerPage

MAY 3, 2021

See Answer. See Answer. Learn something every day ® right from your inbox. Sign up for The Answer of the Day email…. Additionally, studies suggest that the endocannabinoid system modulates taste sensation as well as the metabolism of lipids and glucose. Di Marzo V, Matias I. Nat.Neurosci. 2005; 8: 585-589.

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TheAnswerPage

NOVEMBER 12, 2021

The number of sprays should be gradually increased by 1 spray every other day for the first 4 days and then by 1 spray per day. The number of sprays should be gradually increased by 1 spray every other day for the first 4 days and then by 1 spray per day. See the Answer. mg THC and 2.5

Therapy 59

Therapy Patients Treatment Cannabinoids 59

TheAnswerPage

FEBRUARY 28, 2022

Discontinue products containing disulfiram or metronidazole at least 14 days before starting treatment with Syndros and do not administer these products within 7 days of completing treatment with Syndros.” See the Answer. What component in Syndros interacts with Disulfiram and Metronidazole? metronidazole).

Treatment 52

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TheAnswerPage

OCTOBER 21, 2020

According to 2019 survey results from the NIH’s Monitoring the Future (MTF) study, “the percentage of college students who said they vaped marijuana in the past 30 days rose from 5.2% ” See Answer. ” See Answer. See Answer. in 2017 to 14% in 2019. in 2017 to 17% in 2019.”

Vaping 52

Vaping Marijuana 52

TheAnswerPage

MAY 7, 2021

See Answer. See Answer. Learn something every day ® right from your inbox. Sign up for The Answer of the Day email…. What is the pharmacokinetic profile of marijuana when it is administered rectally? In fact, in human studies, Brenneisen et al. In fact, in human studies, Brenneisen et al. 1996 Oct;34(10)446-52.

THC 59

THC Patients Marijuana 59

TheAnswerPage

SEPTEMBER 11, 2019

Answer of the Day. Answer of the Day. Today’s Answer of the Day. See Answer. See Answer. Today’s Answer of the Day. Today’s Answer of the Day. Today’s Answer of the Day. Today’s Answer of the Day. Leah Roach.

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TheAnswerPage

SEPTEMBER 15, 2019

Answer of the Day. Answer of the Day. Today’s Answer of the Day. See Answer. See Answer. Today’s Answer of the Day. Today’s Answer of the Day. Today’s Answer of the Day. Today’s Answer of the Day. Leah Roach.

Epilepsy 40

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TheAnswerPage

SEPTEMBER 17, 2019

Answer of the Day. Answer of the Day. Today’s Answer of the Day. See Answer. See Answer. Today’s Answer of the Day. Today’s Answer of the Day. Today’s Answer of the Day. Today’s Answer of the Day. Leah Roach.

Epilepsy 40

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TheAnswerPage

SEPTEMBER 10, 2019

Answer of the Day. Answer of the Day. Today’s Answer of the Day. See Answer. See Answer. Today’s Answer of the Day. Today’s Answer of the Day. Today’s Answer of the Day. Today’s Answer of the Day. Leah Roach.

Epilepsy 40

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TheAnswerPage

AUGUST 1, 2020

The cannabinoids (CBD and THC) were injected for 10 to 21 days.). See Answer. See Answer. Do cannabinoid-based medicines impact the deposition of Amyloid ? peptide in Alzheimer’s disease? modifications and inhibit the progression of Alzheimer’s disease. and 50 mg/kg, respectively. (The and 50 mg/kg, respectively.

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Cannabinoids Medicine THC CBD 52

TheAnswerPage

SEPTEMBER 9, 2019

Answer of the Day. Answer of the Day. Today’s Answer of the Day. See Answer. See Answer. Today’s Answer of the Day. Today’s Answer of the Day. Today’s Answer of the Day. Today’s Answer of the Day. Leah Roach.

Epilepsy 40

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TheAnswerPage

SEPTEMBER 16, 2019

Answer of the Day. Answer of the Day. Today’s Answer of the Day. See Answer. See Answer. Today’s Answer of the Day. Today’s Answer of the Day. Today’s Answer of the Day. Today’s Answer of the Day. Leah Roach.

Epilepsy 40

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TheAnswerPage

MARCH 1, 2020

Patients are often instructed not to smoke marijuana for a few days prior to surgery. In the case of chronic marijuana smokers, withdrawal symptoms can develop after just 1 day of not smoking marijuana. See Answer. See Answer. How readily do withdrawal symptoms develop?

Patients 52

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TheAnswerPage

SEPTEMBER 19, 2019

Answer of the Day. Answer of the Day. Today’s Answer of the Day. See Answer. See Answer. Today’s Answer of the Day. Today’s Answer of the Day. Today’s Answer of the Day. Today’s Answer of the Day. Leah Roach.

Cannabinoids 40

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TheAnswerPage

SEPTEMBER 13, 2019

Answer of the Day. Answer of the Day. Today’s Answer of the Day. See Answer. See Answer. Today’s Answer of the Day. Today’s Answer of the Day. Today’s Answer of the Day. Today’s Answer of the Day. Leah Roach.

Epilepsy 40

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TheAnswerPage

FEBRUARY 10, 2022

h after oromucosal spray, 24 h after intravenous administration, 31 h after smoking and 2- 5 days after oral administration. h after oromucosal spray, 24 h after intravenous administration, 31 h after smoking and 2- 5 days after oral administration. See the Answer. administration? After smoking? After oral administration?

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CBD 52

TheAnswerPage

SEPTEMBER 12, 2019

Answer of the Day. Answer of the Day. Today’s Answer of the Day. ” See Answer. See Answer. Today’s Answer of the Day. Today’s Answer of the Day. Today’s Answer of the Day. Today’s Answer of the Day.

Epilepsy 40

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TheAnswerPage

MAY 9, 2021

See Answer. See Answer. See Answer. Learn something every day ® right from your inbox. Sign up for The Answer of the Day email…. Does consuming a high fat/high calorie meal at the same time as you take liquid CBD orally impact the amount of CBD absorbed into the bloodstream? Epidiolex insert [link].

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